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Citrus Fruits




To demonstrate the improved service provided by SYNSYS microprocessor full-leg system compared with a microprocessor-controlled prosthetic knee


A prospective, multicenter, randomized, and crossover study. The results were based on 12 subjects, and the study took place over 4+ years. Over the study, both groups (Study Group 1 and Study Group 2) were visited 4 times. At 4 weeks, Group 1 switched from their usual prostheses to the use of SYNSYS, while Group 2 switched from SYNSYS to the use of their usual prosthesis.

Recruitment Timeline


SYNSYS out-performs the usual prosthesis on flat ground, slope climbing, downhill slope, and stair descent.

Usual prosthesis


Asymptomatic subjects

Ref: Dauriac et al 2015 

*p<0.05 = significant difference

Increased toe clearance due to active dorsiflexion of the toes during swing phase, proven to increase stability and confidence.

Usual prosthesis


*p<0.05 = significant difference

Participants reported better social & physical functioning, better appearance, better rated residual limb health, better rated utility, and lower perceived effort in the 6-minute walk test.

Statistically significant improvement

Using the SF-36 Quality of Life Questionnaire, we tested Physical (PCS) and Mental (MCS) and found that SNSYS users reported both better social functioning and physical functioning. Additionally, on a 12-subscales Prosthesis Evaluation Questionnaire (PEQ), 8 out of 12 improved with SYNSYS and there was a significant improvement in appearance score.


SYNSYS statistically significantly improves daily life, provides users with functional benefits close to a natural gait, and enhances stability and security.

Requena, C et al. (2023, September 18). Increased of stability and security in transfemoral amputees with a knee-ankle synergistic system. Presented at ESMAC. Athens, Greece.

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